Six Ways to Test the Physical Properties of a Tablet

Transforming a formulation into a successful solid dose tablet is a complex process that involves many considerations. Time and raw materials are both valuable and must be saved wherever possible in the production process, and getting production right in the early stages is crucial to prevent expensive faults and tablet defects in the downstream production process.

During compression, the ingredients can have a large effect on physical factors. For example, abrasiveness, moisture content and particle size all affect compressibility. Considerations must also be made of the properties of the finished product.

During their manufacture, tablets are subjected to a great deal of physical abuse within the hopper in which they are spun. During this time, chipping may occur. The extent of this depends on tablet hardness. It is undesirable in terms of product quality and is also a potential health risk to the consumer.