OCULAR DELIVERYTreatment of some diseases is best achieved by direct administration near the affected area, particularly with diseases involving ophthalmic, optic, dermal, oral cavity, and anorectal tissues.
Ocular drug delivery is an interesting and challenging opportunity for pharmaceutical development. The eye is protected by a series of complex defense mechanisms, which usually result in poor bioavailability of drugs administered via the ocular route. These include tear production and the blinking reflex in addition to short residence time and reduced drug permeability.
