How to measure and analyse the texture of food, cosmetics, pharmaceuticals and adhesives.

Thursday, 13 November 2014

Texture Analysis in action: the Miniature Kramer/Ottawa Cell

Mini Ottawa cell test on a TA.XTplus Texture AnalyserThe MINIATURE KRAMER SHEAR/OTTAWA CELL (HDP/MK05* or HDP/MKS*) is particularly suited to reduce the force of bulk shearing/compression of multi particle products or non-uniform products.

It attaches to the HDP/90 Heavy Duty Platform. A 5-bladed head or compression platen can be attached to the arm of the texture analyser depending upon whether a shearing or bulk compression/extrusion test is required.

Tuesday, 11 November 2014

Tips and tricks for mucoadhesion testing

Stretching spaghetti from the bowlMucoadhesion is the process by which a drug delivery device is designed to stick to a part of the gut or other mucosae, thus delivering drug to a precise site in the body for an extended period.  

This gives more effective treatment of some diseases and can also protect drugs from some of the harsh conditions in the body. Mucoadhesive drug delivery systems are used to treat several conditions in the mouth and have been investigated as treatments for stomach ulcers and cancer. 

The majority of infections affecting man and animals take place or start in mucous membranes. The ability to retain pharmacologically-active agents for extended periods of time on any mucosal epithelium, including those of the nose, mouth, rectum or vagina confers several potential therapeutic advantages.