How to measure and analyse the texture of food, cosmetics, pharmaceuticals and adhesives.

Thursday, 20 August 2015

Texture Analysis in Action: the Ice Cream Scoop and Ice Cream Cone Support Rig

Ice cream scoop force test using the TA.XTplus Texture Analyser Two of our test attachments have been designed specifically for use in the development of frozen confectionery.

The ICE CREAM SCOOP (A/ICS) is used to measure the scooping resistance of ice cream, and other similar samples which can be formed into a self-supporting block.

A tilt-table is mounted on to the base of the Texture Analyser and the scoop positioned onto the load cell.

Tuesday, 18 August 2015

Ensuring consistent quality in Rectal Delivery Products

Holding a gel capsule
Although administration via the peroral route is the most commonly targeted goal of new drug and dosage form research and development, oral administration is not always feasible or desirable. 

The potential for oral dosage form development is severely limited for active agents that are poorly absorbed in the upper gastrointestinal (GI) tract and unstable to proteolytic enzymes. Some agents cause local stomach or upper GI irritation or require doses in excess of 500mg. Additionally, treatment of some diseases is best achieved by direct administration near the affected area, particularly with diseases involving anorectal tissues. 

Although oral administration can be used for drugs targeted for some of these diseased tissues, exposure of the entire body compartment to the administered drug is inefficient and can lead to undesired adverse effects.