INTRODUCTION
The latest craze to sweep the pharmaceutical industry is one of controlled-release drug delivery systems.
This
controlled release can be systemic (generally via the bloodstream), as
is generally the case for oral preparations, or act specifically at the
site of greatest benefit (for example, in implanted devices) and these
dosage forms are defined as preparations that modify the rate and/or the
time and/or site of release of the active ingredient, in order to
achieve specific therapeutic objectives which cannot be achieved with
conventional dosage forms similarly administered.